Patients with hematuria had significantly lower renal function, a

Patients with hematuria had significantly lower renal function, and the prevalences of nephrotic syndrome and retinopathy were significantly higher than in patients without hematuria. Interestingly, based on a logistic selleck compound regression analysis, the presence of nephrotic syndrome and a known duration of diabetes were identified as significant predictors for hematuria with diabetic nephropathy. Concluding remarks and future directions Deep insights into the onset and progression of albuminuria along with GFR may elucidate the pathogenesis of progressive kidney complications and Cell Cycle inhibitor associated cardiovascular diseases. Further studies of the clinical characteristics and the pathological findings

of kidney involvement in patients with diabetes are required for a better understanding of diabetic nephropathy and the benefits of therapy for it. Acknowledgments This study was supported in part by a Grant-in-Aid for Diabetic Nephropathy Research from the Ministry of Health, Labour and Welfare of Japan. References 1. Nakai S, Suzuki K, Masakane I, Wada A, Itami N, Ogata S, et al. Overview of regular dialysis treatment in Japan (as of 31 December 2008). Ther Apher Dial. 2010;14:505–40.PubMedCrossRef 2. Nakayama M, Sato T, Sato H, Yamaguchi Y, Obara K, Kurihara I, et al. Different

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