The mean age was 6.5 Selleckchem RSL 3 years. The seizures’ duration ranged from 6 months to 2 years. The histopathological examination of the resected lesions revealed
in 12 cases the presence of a ganglioglioma, in 7 cases dysembryoplastic neuroepithelial tumor, in I case a low grade glioma, in 2 cases cortical dysplasia, and in 2 cases cavernous malformations. In 18 cases, the lesions were located in the temporal lobe and in 6 cases the lesions were extratemporal. After a mean follow-up period of 4.4 years, 79% (19/24) of patients were seizure free. There were no permanent neurological deficits or deaths. surgery for focal epilepsy in children is a safe procedure with favorable results.”
“Introduction and objectives. Echographic studies of the composition of atheromatous plaque make use of the median gray level, which provides an overall measure of echogenicity. We propose adding an additional dimension to this approach by dividing the lesion into layers and generating a curve that shows the variation in echolucency with depth.
Methods. Femoral and carotid plaque in asymptomatic patients was investigated using both the median
gray level and new layer methods. Interobserver variability was assessed for both methods. Three risk factors were studied: age, gender and smoking status. Differences in echogenicity-depth curves between different groups were assessed using two-way ANOVA.
Results. The two methods gave similar results for the mean echogenicity of carotid and femoral plaque. Echogenicity Saracatinib inhibitor increased as a function of depth
(r=0.96; P<.001). With the median gray level method, none of the risk factors produced a change in echogenicity. However, with the layer method, the echogenicity of femoral plaque was found to increase with age (P<.001), though gender had ne effect. Moreover, the echogenicity of superficial layers was less in smokers than nonsmokers (P<.01). In carotid plaque, echogenicity increased with age (P<.01) and was higher in men (P<.01). The echogenicity of deep plaque was greater in smokers than nonsmokers (P<.05). The reproducibility BIIB057 mw of the two methods was similar.
Conclusions. The layer method was more effective than the median gray level method for identifying the effect of age, sex and smoking status on the echogenicity of atheromatous plaque.”
“Purpose Health-related quality of life (HRQoL) and unmet needs (needs) questionnaires offer alternative perspectives for assessing cancer patients’ concerns. We examined whether the conceptual differences underlying these alternative approaches yield corresponding empirical differences.
Methods Eight-hundred and seventy-four women with ovarian cancer completed the Functional Assessment of Cancer Therapy scale (FACT-G; HRQoL) and the Supportive Care Needs Survey (SCNS-SF34; needs) every 3 months for 2 years.