Differences

in patient demographics, ancillary clinical investigations and outcomes between patients tested by POCT and Vactosertib cost those in comparator wards tested in the laboratory are shown in Table 1. There were no significant differences in terms of length of stay and all-cause see more mortality rates. Overall 30-day all-cause mortality rate was 5.1 per 1,000 inpatient days (25.3%), which is slightly less than that reported elsewhere [20]. Older persons’ patients who had POCT were significantly less likely to have a test requested for bacterial stool culture ZD1839 (3.1% vs. 10.9% p = 0.044). This difference was not observed in the ICU patients. No other differences in ancillary test requesting were observed.

Table 1 Patient demographics, ancillary clinical investigation requesting and clinical outcomes for patients tested with POCT and laboratory-based testing only   Older persons patients ICU patients Combined patients Tested with POCT (Group 1) Laboratory-based testing (Group 2) p value Group 1 vs. Group 2 Tested with POCT (Group 3) Laboratory-based testing (Group 4) p value Group 3 vs. Group 4 Tested with POCT (Group 5) Laboratory-based testing (Group 6) p value Group 5 vs. Group 6 n 97 92   233 227   330 319   Male (%) 36/97 (37%) 34/92 (37%)

1.0 151/233 (65%) 149/27 (66%) 0.922 187/330 (57%) 183/319 (57%) 0.7898 Mean age (years; SD) 85 Cell press (8) 84 (7) 0.7566 59 (18) 61 (17) 0.1120 66 (20) 68 (18) 0.3002 Number (%) testing positive 14 (14.4%) 16 (17.4%) 0.6912 16 (6.9%) 15 (6.6%) 1.0 30 (9.1%) 31 (9.7%) 0.7898 Median day of testing (days; Interquartile range) 9 (4–20) 9 (5–20) 0.7107 11 (4–20) 9 (4–21) 0.8257 10 (4–20) 17 (8–38) 0.9416 Number (%) hospital onset 81 (84%) 89 (97%) 0.003 202 (87%) 196 (86%) 1.0 283 (86%) 285 (89%) 0.1915 Median length of stay after sample (days; interquartile range) 11 (7–22) 13 (6–28) 0.5806 18 (9–43) 22 (10–45) 0.2808 30.5 (42) 28.2 (27.2) 0.4140 Number (%) where plain abdominal X-ray performed 6 (6.2%) 3 (3.3%) 0.4985 3 (1.3%) 7 (3.1%) 0.2161 9 (2.7%) 10 (3.1%) 0.8187 Number (%) where abdominal CT/MRI or USS performed 4 (4.1%) 5 (5.4%) 0.7423 2 (0.9%) 7 (3.1%) 0.102 6 (1.8%) 12 (3.8%) 0.1552 Number (%) where sigmoidoscopy/colonoscopy performed 2 (2.1%) 1 (1.1%) 1.0 1 (0.4%) 0 1.0 3 (0.9%) 1 (0.3%) 0.6241 Number (%) where bacterial stool culture performed 3 (3.1%) 10 (10.9%) 0.0444 9 (3.9%) 6 (2.6%) 0.6016 12 (3.6%) 16 (5%) 0.4424 Number (%) where norovirus investigation performed 12 (12.4%) 12 (13%) 1.0 7 (3%) 7 (3.1%) 1.0 19 (5.8%) 19 (6%) 1.0 30-day all causes mortality rate per 1,000 inpatient days 6.25 7.91 0.5387 4.76 5,75 0.3854 5.1 6.27 0.