Conversion to laparotomy during minimally invasive colorectal surgery has been reported to be as high as 29%, and it has been associated with slow recovery and high postoperative morbidity [1, 18]. In our series, one case required conversion to open surgery and occurred in the MIS group and was due to difficult dissection and exposure in the setting Ceritinib LDK378 of a large, bulky tumor. In the SILC group, although there were no conversions to open surgery, five cases required conversion to HALC. Despite the challenges of the SILC approach, our conversion rate to laparotomy is low, which is consistent with other SILC studies [10, 11, 17]. In challenging SILC cases, a minimally invasive platform may be maintained by the placement of additional ports or conversion to HALC [8].

The HALC technique has become our preferred modality for conversion, as it is readily available requiring only an extension of the incision. Furthermore, it offers the advantages of an enhanced exposure, blunt digital dissection, and the confidence provided by the hand-assistance, which is particularly beneficial early in the learning curve. Additionally, the HALC approach results in outcomes similar to those of other MIS techniques and improved as compared to open surgery and thus the patients attain the benefits of a minimally invasive platform and the enhanced recovery measures. In our practice, we now favor the single-incision approach as the MIS option for the majority of colon resections. Although morbid obesity may be a factor predicting conversion, it is not an absolute contraindication of SILC [8].

We have found, however, that for those with a BMI of 35 or greater, the SILC approach is less ideal and the benefits to the patient may not outweigh the technical challenges of the procedure. Reported data typically shows that the SILC approach results in nearly identical or shorter LOS, as compared to CLC [10]. In the present study, the mean LOS in the SILC group was slightly longer than that of the MIS group; yet this difference was not statistically significant. This difference may be attributed to an overall low Batimastat number of cases, and thus a sampling error. Furthermore, we are comparing a relatively new procedure comprising the initial surgeons’ experience to techniques in which we had performed over one hundred cases. In this series, the overall complication rate was 12% and was similar between the SILC and MIS groups. In the SILC group, the most common complication was wound infection (n = 2), followed by anastomotic leak (n = 1), para-anastomotic abscess (n = 1), prolonged postoperative ileus (n = 1), stroke (n = 1), and respiratory failure (n = 1).