As shown in Figure 3a, absorption peaks at around 637, 592, and 451 cm-1 corresponding to the Fe-O stretching are observed. The characteristic peaks of Fe-O of the copolymer-capped Fe3O4 are found to shift towards the short-wavenumber region (blueshift) in comparison with those of typical uncapped

Fe3O4 particles. Furthermore, 3-Methyladenine datasheet obvious peaks at around 1,640, 1,550, and 3,030 cm-1 are detected which are characteristic peaks of -C = C- stretching and = C-H vibration of benzene ring, respectively. In addition, absorption peaks at about 3,432, 1,718, and 1,074 cm-1 selleck products deriving from -OH, -C = O, and -C-O- vibrations of -COOH, respectively, are also observed. Moreover, characteristic peaks at about 2,921 and 1,409 cm-1 originating from -CH3 of oleic acid chains are detected as well. The FTIR results apparently indicate that Fe3O4 nanoparticles are successfully capped by the AA/St grafting copolymers. After the grafting copolymerization, the copolymer-coated Fe3O4 nanoparticles can spontaneously precipitate rather than dissolve in hexane. This phenomenon can also confirm the formation of the copolymer-capped Fe3O4 nanoparticles to some

extent because of the bad miscibility between the non-polar hexane and the copolymers. It is shown in Figure 3b that characteristic peaks of a typical doped PANI in the scales of <350, 400 to 500, and 500 to 700 nm corresponding to π-π*, polaron-π* (trans), and polaron or bipolaron transitions, EGFR inhibitor respectively, are detected [10, 26], revealing the achievement of the PANI-capped Fe3O4 nanoparticles. However, there is an obvious redshift of the characteristic absorption peaks from (421 and 608 nm) in comparison with traditional inorganic

acid-doped PANI, which is the comprehensive result of p-TSA and macromolecular poly(acrylic acid)-doped PANI. The obtained PANI chains probably form more extended conformations. Figure 3 Spectra of (a) FTIR of cografting polymer-coated Fe 3 O 4 and (b) UV–vis of PANI/Fe 3 O 4 nanoparticles. Figure 4a illustrates the morphology of oleic acid-coated Fe3O4 nanoparticles prepared by the coprecipitation method. It can be seen that Fe3O4 pre-spheral nanoparticles with a size range of 5 to 15 nm are found evenly dispersed into the transmission electron microscopy (TEM) view and that the size distribution of the Fe3O4 nanoparticles is relatively narrow. Most of the Fe3O4 nanoparticles own a size near 10 nm, and the distance between two near particles is only in the scale of 1 to 2 nm, showing a pre-monodispersity. After capping with the in situ polymerized PANI, both the size range and the shape of the Fe3O4 nanoparticles are changed (see Figure 4b).