8213). In patients with refractive results close to emmetropia, the mean AL x K was 1005.91 +/- 25.88 (SD), meaning that in the range of 954 and 1058, there was a 95% possibility
that the patients were almost fully corrected. The following regression formula was obtained to calculate the amount of refractive error independent of cataract onset: Refractive error = -0.0157 x (AL x K) + 16.437.
CONCLUSIONS: The regression formula determined whether the refraction depended on the onset of cataract and estimated the amount of undercorrection or overcorrection that occurred after refractive surgery, leading GNS-1480 to improved estimation of the power of the IOL to be implanted. It may allow the use of history-related formulas in IOL power calculation TPX-0005 research buy for eyes that have had corneal refractive surgery.”
“Background: Agonist replacement treatment is a promising strategy to manage cannabis-use disorders. The aim of
this study was to assess the combined effects of the synthetic cannabinoid agonist nabilone and Delta(9)-tetrahydrocannabinol (Delta(9)-THC) using drug-discrimination procedures, which are sensitive to drug interactions. Testing the concurrent administration of nabilone and Delta(9)-THC was also conducted to provide initial safety and tolerability data, which is important because cannabis users will likely lapse during treatment.
Methods: Six cannabis users learned to discriminate 30 mg oral Delta(9)-THC from placebo and then received nabilone (0, 1 and 3 mg) and Delta(9)-THC (0, 5, 15 and 30 mg), alone and in combination. Subjects completed the multiple-choice procedure to assess
drug reinforcement, and 发现更多 self-report, task performance and physiological measures were collected.
Results: Delta(9)-THC and nabilone alone shared discriminative-stimulus effects with the training dose of Delta(9)-THC, increased crossover point on the multiple-choice procedure, produced overlapping subject ratings and decreased skin temperature. Nabilone alone also elevated heart rate. In combination, nabilone shifted the discriminative-stimulus effects of Delta(9)-THC leftward/upward and enhanced Delta(9)-THC effects on the other outcome measures.
Conclusions: These results replicate a previous study demonstrating that nabilone shares agonist effects with the active constituent of cannabis in cannabis users, and contribute further by indicating that nabilone would likely be safe and well tolerated when combined with cannabis. These data support the conduct of future studies to determine if nabilone treatment would produce cross-tolerance to the abuse-related effects of cannabis and reduce cannabis use. (C) 2010 Elsevier Ireland Ltd. All rights reserved.”
“Xanthomonas citri subsp citri (Xac) is the bacterium responsible for citrus canker disease in citrus plants.