6%), 14 (9.2%), 28 (18.4%), and seven (4.6%) patients had gestational hypertension, chronic hypertension, preeclampsia, and preeclampsia superimposed on chronic hypertension, respectively, during the peripartum period. Twenty-two patients (14.5%) developed postpartum eclampsia, and more than 90% of these patients presented within 7 days after discharge from the hospital. The most common presenting symptom was headache in 105 (69.1%) patients. Patients who developed eclampsia were significantly younger than those who did not (mean +/- standard deviation, 23.2 +/- 6.2 compared KPT-8602 with 28.3 +/- 6.7 years; adjusted odds ratio [OR] 1.13, 95% confidence interval [CI] 1.02-1.26, P=.03),
and other demographic variables were no different. A lower readmission hemoglobin was associated with a lower odds of progression to eclampsia selleck compound (10.7 +/- 1.7 compared
with 11.6 +/- 2.2 g/dL, adjusted OR 0.75, 95% CI 0.57-0.98, P=.04).
CONCLUSION: One week after discharge appears to be a critical period for the development of postpartum eclampsia. Education about the possibility of delayed postpartum preeclampsia and eclampsia should occur after delivery, whether or not patients develop hypertensive disease before discharge from the hospital. (Obstet Gynecol 2011;118:1102-7) DOI: 10.1097/AOG.0b013e318231934c”
“Objective: To report an extremely rare case of thyroid tuberculosis (TT) with abnormal thyroid function and to review the related literature.
Methods: We present the patient’s history, clinical findings, laboratory selleck test results, imaging examinations, cytological data, management, and follow-up. In addition, we perform a review of the previously published cases of TT and give special attention to those with hypothyroidism.
Results: A 45-year-old Indian man presented to the outpatient clinic with neck swelling and respiratory and constitutional
symptoms. Cervical ultrasound revealed a thyroid nodule and a necrotic right cervical adenopathy. Fine-needle aspiration cytology (FNAC) was performed and purulent material was removed from thyroid and lymph node. In both specimens, the culture was positive for Mycobacterium tuberculosis complex, and a cytological examination revealed epithelioid cell granulomas and necrosis. Mycobacterium tuberculosis complex was also identified by sputum culture. Antibiotic testing revealed sensitivity to all first-line drugs. A diagnosis of disseminated tuberculosis with thyroid and cervical lymph node involvement was made. Thyroid function was consistent with subclinical hyperthyroidism that subsequently evolved to hypothyroidism, requiring thyroid hormone replacement, and reflected tuberculous thyroiditis. Antituberculosis drugs were started with good therapeutic response.
Conclusion: TT is a rare condition and its association with thyroid function abnormalities is even rarer.